The small unincorporated town of Nobleton was probably first settled in the late 1800s along the banks of the Withlacoochee River in Citrus County. The primary economic drivers were no doubt the abundand timber resources and the making of turpentine.

As the initial timber boom began to slow, the community pivoted toward local commerce and catering to travelers navigating the river or the rural roads. In 1920, a general store was constructed right on the banks of the Withlacoochee River. This building became the community's primary gathering place, where residents bought dry goods, swapped news, and watched boats travel along the water. Miraculously, this structure survived the decades and still stands today as the Historic River Oaks Landing, serving as the oldest commercial building in the town.

In February of 1925, Harry Nobles began a housing development at the site, and in July of that year a post office was established using the name "Nobleton". Within a year, Nobles had constructed 90 homes, a water system had been installed, and a few of the roads were paved. Within a few years, the town had a hardware store, a grocery, and a lumber yard. Henry Plant's railroad was built along the southern border of the town in the late 1800s, but no station was ever built for Nobleton. County Road 476 - known as Lake Lindsey Road - is the primary highway through the town.

Today, Nobleton is still about the same size as it was when it was developed by Harry Nobles. The close-knit neighborhood has a community center building, an historic church established in 1928, and a restaurant. It remains connected to the Withlacoochee River with its Nobleton Wayside Park, which includes a boat ramp and kayak launch, picnic grounds, and other public amenities. Tourist traffic to Nobleton has benefited in recent years due to its close proximity to the Withlacoochee State Trail, which now follows the path of the old railroad right-of-way.